Effect of novel vitamin D receptor activator paricalcitol on renal ischaemia/reperfusion injury in rats
نویسندگان
چکیده
منابع مشابه
The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide ad...
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چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولParicalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling.
Inflammation is a pathologic feature of a variety of chronic kidney diseases. Several lines of evidence suggest a potential anti-inflammatory role for vitamin D in chronic kidney disease, but the underlying mechanism remains unknown. Here, the effect of the synthetic vitamin D analogue paricalcitol on renal inflammation was investigated in a mouse model of obstructive nephropathy. Paricalcitol ...
متن کاملCombination Antioxidant Effect of Erythropoietin and Melatonin on Renal Ischemia-Reperfusion Injury in Rats
Objective(s): Renal ischemia reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal IR. The purpose of this study was to investigate the effect of co-administration of melatonin (MEL) and erythropoietin (EPO), potent antioxidant and ...
متن کاملRenal actions of vitamin D in D-deficient rats.
COSTANZO, LINDA S., PAUL R. SHEEHE, AND Il. M. WEINER. Renal actions uf uitamin D in D-dqkient rats. Am. J . Ph ysiol. 226 (6) : 1490-1495. 1974.-The renal clearances of calcium and phosphate were studied in vitamin D-deficient rats and similar rats repleted with 100 U of vitamin D 48 h prior to the experiments. Thyroparathyroidectomy (T-PTX) was performed on all animals immediately before the ...
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ژورنال
عنوان ژورنال: The Annals of The Royal College of Surgeons of England
سال: 2013
ISSN: 0035-8843,1478-7083
DOI: 10.1308/003588413x13629960049117